To conduct an effective self-experiment with any skincare regime change, we recommend that you locate some nearby skin clinics and ask them if they operate a Visia Scanner.

LB: That's a grand vision and will get our readers very excited. You just talked about skin aging, hair loss, fat tissue, and these being driven by cellular senescence. This all fits into a bigger picture for longevity technologies over the next decade and more. I'm almost 48 years old, I'm a woman, so hormones can be a bugbear. So really, I'm a supplement queen, I love my supplements, and most of them are adrenaline balancing and hormone balancing for me means iodine to make sure my thyroid is taken care of, vitamin B for stress levels, otherwise, those hormones really throw my skin out. The consequence of that is that your skin will look better. Our primary focus is on the health of the skin. That's why we like to use skinspan instead of other classic cosmetic terms. Why does skin age?This is one of the things I LOVE about NextHealth. They, like me, are obsessed with optimising human performance. In the 30 minutes following my scan, Matthew diligently and patiently answered my many questions about how I can work to improve the apparent youthfulness of my skin. Human skin is made up two major layers - the dermis and the epidermis. We reconstruct both of these layers in the lab and then test products on that skin. LB:And to that point, the name of your company is actually based on some science, you've got this number in there - “ 818”. There's a fascinating scientific story behind where that number comes from. Could you tell us about that? What is known however, is that UV damage, so called ‘ photoaging’, reduces telomere length as damage from sun exposure is accumulated. More recently, telomere attrition in the skin has been linked to significant increases in skin cancer risk. It’s one thing to claim you can reverse skin aging, another to suggest you can halt or reverse cellular senescence in the skin.

Glucoside, Cocamidopropyl Hydroxysultaine, Cocamidopropyl Betaine, Dimethyl Sulfone (MSM), Sodium Ascorbyl Phosphate (Vitamin C), Cocamide MIPA, Organic Aloe Barbadensis Leaf Juice (Aloe Vera), Olea Europaea Fruit (Organic Olive) Oil, Rosa Canina Seed (Organic Rosehip Seed) Oil, Borago Officinalis (Borage) Oil, Olea Europaea Fruit (Organic Olive) Oil, Citrus Aurantium Dulcis Extract (Orange Peel) Extract, Origanum Vulgare (Oregano) Extract, Tocopheryl Acetate (Vitamin E), Melaleuca Alternifolia (Tea Tree) Oil. Equisetum Arvense Extract (Horsetail Extract), Taraxacum Officinale Extract (Dandelion Extract), Organic Centella Asiatica Extract (Gotu Kola Extract), Geranium Maculatum Extract (Wild Geranium), Citrus paradisii (Pink grapefruit) oil Phenoxyethanol, Disodium Lauryl Sulfosuccinate, Disodium Laureth Sulfosuccinate, Acrylates/C10- 30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin. Add to that narrative for us a bit. Where do you think this industry is going, led by visionary CEOs like yourself? Look at the 5 to 10 year horizon, tell us what you see. But they don't stop to ask, what's the starting base of this? Where's the science? What does ageing look like in the skin? How do cells age? And then let's go from there. So everything we do, is based on science, not a trend, and not something that we read from someone else. What is TAM 818?

Pleased With Everything

More than just looking to improve the appearance of the skin, we want to extend the time that your skin is healthy and functional. There's some really interesting details here – for example, your team uses actual human skin - we want to know more about this. Phrases such as “3D human skin equivalents”, or “human cell based platform” jump out at us. You're using these tools to study the aging process. Tell us more. Stop accidentally ageing your skin by using products that damage, thin your skin and accelerate ageing through increased cell division. One Truth 818 with TAM-818 is the only way to combat topical ageing.

Carolina - thank you so much for sitting down with us today and sharing all of the amazing things happening at OneSkin. With that we can close it off! When we are young, we have DNA repair enzymes that fix this damage. But as we get older, that system becomes deficient. And that’s where we come in. We believe that your aesthetic age is an investment, worth your hard earned dollars. But you have to be smart about it! We help you do just that. How do you suggest the serum is used with other products? Do we still need a moisturiser, eye cream and antioxidant serum? They form as a result of UV damage, as the melanin coagulates beneath the skin surface, and will eventually lead to visible damage at the skin’s surface and are a sure sign that collagen is also being degraded.LB:The discovery of this telomere activating molecule 818 - it has become a fundamental ingredient in your product line. Naturally, we're all very curious. Now we know this is your IP, this is your secret sauce, but what can you tell us about TAM 818? We're fascinated and curious here, Rachael. So, while more science is needed to have ‘all the answers’, this is common in the longevity technology sphere. As we look out for our long-term health, we get to choose how far ahead of the ‘proven’ science we individually are comfortable to reach. Secondly, this concept of “ skinspan”, which sounds closely related to healthspan. These are new concepts to our readers- tell us about them.