Maxtra is a direct-acting sympathomimetic which has vasoconstrictor effect on mucosal blood vessels when applied topically and in turn reduces oedema of the nasal mucosa. Important information about Chlorphenamine (Piriton)- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 23 April 2019]. Available from: In rats, the oral LD 50 is 680 ug/kg and the subcutaneous LD 50 is 1630 ug/kg. In mice, the oral LD 50 is 4700 ug/kg, the intraperitoneal LD 50 is 48 mg/kg, and the subcutaneous LD 50 is 34 mg/kg. Maxtra Syrup 60 ml can be taken with or without food in a dose and duration as advised by the doctor. The most common side effects of Maxtra Syrup 60 ml are drowsiness, dizziness, headache, dry mouth/nose/throat, upset stomach, constipation, or trouble sleeping.Most of these side effects of Maxtra Syrup 60 ml do not require medical attention and gradually resolve over time. however, if the side effects are persistent, reach out to your doctor.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert. Ans : It is an antihistamine which restricts the action of histamine and work as a reliever from the symptoms such as Sinus pressure, Sinus congestion, Running nose, Throat itching, Hay fever, Allergies, sneezing because of respiratory infections, Watering eyes, Cough. Ans : This syrup should be used on the basis of severity of symptoms or as consulted by the doctor. There are some advised dose for the children of 2 to 6 years of age is 2.5 - 5 ml every hours and 5 - 10 ml every hour for the children above 6 years of age. And all the doses should be given in a proper measured manner with a measuring cup. For the best results it should be given at evenly spaced intervals. To see the full effect of medicine, it can take more than 6 hours or even more than 2 days in some cases. Therefore, it is advisable that you change your dosage according to your interaction with the syrup. Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Ans : No, Maxtra is unsafe to use in pregnancy. Patient can consult doctor for an alternative medication. Apart from this, high blood pressure, seizures, overactive thyroid, stomach problems or urination problems also. Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution; prolonged use will cause significant xerostomia. There is no sufficient information about the possible side effects of how this syrup can affect breastfeeding women in general. Therefore, you must consult your doctor before consumption.

Maxtra binds to α 1- and α 2-adrenoceptors, which are Gq-protein-coupled receptors that promote vascular smooth muscle contraction by increasing intracellular calcium levels in response to ligand activation. Maxtra Syrup 60 ml contains Chlorpheniramine and Phenylephrine. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Phenylephrine is a decongestant that narrows the small blood vessels, relieving the nose's congestion or stuffiness. Together, Maxtra Syrup 60 ml effectively reduces allergic symptoms. Maxtra Syrup 60 ml belongs to the combination medication called 'anti-allergics' primarily used to treat symptoms caused by the common cold, flu, allergies and other breathing problems like sinusitis and bronchitis. An allergy is an immune system response to foreign elements typically not harmful to your body. These foreign elements are known as 'allergens.' Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever. At the same time, others might be allergic to pollen or pet dander. Maxtra is an adrenergic α1- and α2-agonist and a direct-acting sympathomimetic drug. By stimulating adrenergic receptors, oxymetazoline causes vasoconstriction of dilated arterioles and reduces blood flow. In a radioligand competition study, oxymetazoline displayed higher affinity at α1A-adrenoceptors compared to α2B-adrenoceptors, but with higher potency at α2B-adrenoceptors. When sprayed intranasally, oxymetazoline relieved relief nasal congestion and improved nasal airflow in patients with acute coryzal rhinitis for up to 12 hours following a single dose. Imidazole derivatives such as oxymetazoline are readily absorbed across mucosal membranes, especially in children. In adult subjects with erythema associated with rosacea, the mean ± standard deviation (SD) C max was 60.5 ± 53.9 pg/mL and the AUC from time 0 to 24 hours (AUC 0-24hr) was 895 ±798 pg x hr/mL following topical administration of first-dose oxymetazoline. Following once-daily topical applications for 28 days, the mean ± SD C max was 66.4 ± 67.1 pg/mL and the AUC 0-24hr was 1050 ± 992 pg x hr/mL. Following twice-daily applications for 28 days, the mean ± SD C max was 68.8 ± 61.1 pg/mL and the AUC 0-24hr was 1530 ± 922 pg x hr/mL.Phenylephrine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from: Two-litres+: for families, those who drink lots or if you don’t want to keep refilling the jug throughout the day This medicine provide temporary relief of nasal congestion and eustachian tube congestion along with the associated symptoms. Maxtra Syrupmay cause drowsiness. Avoid driving or operating machinery while taking this medication.

Maxtra Syrup is primarily prescribed to treat common cold. This is a combination syrup that has Chlorpheniramine and Phenylephrine as active ingredients. It also relieves the associated symptoms such as runny nose, itching of the throat and nose, watery eyes, and sneezing due to upper respiratory infections.You should avoid driving whenever possible if you are under this medication. It may cause drowsiness or dizziness in some cases, which can affect your driving skills.

Ans : It is a combination of two different drugs (Chlorpheniramine 2 mg/ml, Phenylephrine 5 mg/ml) which used to treat conditions such as Nasal De-congestion, Common cold and Flu-like symptoms. Following single-drop ocular administration of oxymetazoline in healthy adult subjects, the mean ± SD C max was 30.5 ± 12.7 pg/mL and the area under the concentration-time curve (AUC inf) was 468 ± 214 pg x hr/mL. The median T max was 2 hours, ranging from 0.5 to 12 hours. It is important that you must discuss about your medical history in general whenever you consult a doctor. Ask your doctor whether you are fit to consume this medication or not as the medication can affect the functioning of kidney in some cases, especially if you are already suffering from kidney related issues. Ans : There are some side effects of this syrup. It can cause some other allergies or unwanted effects. Some of them are: Nausea, Irregularity of heartbeats, Vomiting, Increased heart rate, Headache, Palpitations, Constipation, Stomach ache, Blurred vision, Swelling of face, Shortness of breath, Loss of consciousness. The answer to this question very much depends on the brand and model of your water filter jug. It also depends on how often you’re using it. Some water filters come with indicators to let you know it’s time to change it, which is useful. But, all new water filters will let you know how long the filter is supposed to last, this is typically displayed in months and filters can last anywhere from two to six months.

Easy to clean, fill and handle

If you can’t remember when you last changed your filter, look out for these signs that the filter needs replacing: