New box on G proteins, proteins that regulate their GTPase activity, and the medical consequences of defective G protein function Migration Tool to move your assignments from your previous Sapling Course into your new Achieve course

Mitochondrial Genes: Their Origin and the Effects of Mutations Photosynthesis: Harvesting Light Energy New section on pharmaceuticals developed from an understanding of enzyme mechanism, using penicillin and HIV protease inhibitors as examples Tools for understanding are provided including ‘Key Conventions’ and ‘Special Themes’ (Metabolic Integration, Obesity, and Diabetes, Evolution) as well as ‘Medical Insights and Applications-Icons’ used throughout the book denote material of special medical interest and updated to reflect the most current content. The summary of principals and the highlighting of these principals throughout the text. This is really helpful! The Boxes with additional information, particularly clinical relevance of the material. Most of my students are pre-med and it helps them engage in the material better if there is clinical relevance. The problems at the end of the chapter. These are really beneficial for the students who want to make sure they understand the material." --Robin Haynes, Harvard University

This edition provides a new learning path for students, through emphasis on the fundamental principles of biochemistry. Lehninger Principles of Biochemistry, 8e continues to help students navigate the complex discipline of biochemistry with a clear and coherent presentation. Renowned authors David Nelson, Michael Cox, and new co-author Aaron Hoskins have focused this eighth edition around the fundamental principles to help students understand and navigate the most important aspects of biochemistry. Text features and digital resources in the new Achieve platform emphasize this focus on the principles, while coverage of recent discoveries and the most up-to-date research provide fascinating context for learning the dynamic discipline of biochemistry. Interactive Metabolic Map and Animated Mechanism Videos, problem-solving videos, and case studies are integrated into Lecture Slides and available as stand-alone resources Expanded discussion of blood pH buffering by the bicarbonate system,including a new box describing Haldane's use of himself as a guinea pig in experiments aimed at changing the acidity of blood

Question Bank with thousands of additional questions to create an assignment from scratch or add to a curated assignment Insights on top learning objectives and assignments to review are surfaced just-in-time (7 day period) New section on emerging role of ribulose 5-phosphate as central regulator of glycolysis and gluconeogenesisAll content has been streamlined so the text is focused on what is most important and useful to modern students and for future reference, and organized around principles for better understanding, providing a new learning path for students, through the emphasis on the fundamental principles of biochemistry.

New medical box, introduces hemoglobin glycation and AGEs and their role in the pathology of advanced diabetes Biochemistry: Concepts and Connections (2nd Edition) By Dean R. Appling, Spencer J. Anthony-Cahill and Christopher K. Mathews Available for the first time in Achieve, the definitive reference text for biochemistry Lehninger Principles of Biochemistry, 8e helps students focus on the most important aspects of biochemistry-- the principles! Dave Nelson, Michael Cox, and new co-author Aaron Hoskins identify the most important principles of biochemistry and direct student attention to these with icons and resources targeted to each principle. A design guided by learning science research. Co-designed through extensive collaboration and testing by both students and faculty including two levels of Institutional Review Board approval for every study of AchieveThe ‘Interactive Metabolic Map’ allows students to navigate and zoom between overviews and detailed views of the most commonly taught metabolic pathways. Embedded Tours take students through the pathways step-by-step, helping them to both visualize concepts in isolation and understand how concepts are connected. By examining the pathways in this way, students are better equipped to understand the meaning of those connections. Animated Techniques are short animations of laboraatory techniques. Designed to provide students with an overview of protocol, these animations give students a conceptual understanding of what is happening at the chemical level.

New section, Chemical logic and common biochemical reactions, discusses common biochemical reaction types Mechanism Figures features step-by-step descriptions to help students understand the reaction process.

New descriptions of volatile lipids used as signals by plants, and pigments of bird feathers derived from colored lipids in plant foods New medical box on how the high rate of glycolysis in cancerous tissue aids cancer diagnosis and treatment