Gorski, Julian et al. “Dexpanthenol in Wound Healing after Medical and Cosmetic Interventions (Postprocedure Wound Healing).” Pharmaceuticals (Basel, Switzerland) vol. 13,7 138. 29 Jun. 2020, doi:10.3390/ph13070138 Centella Asiatica Extract offers antioxidant benefits with soothing properties that help reduce inflammation, especially on acne-prone sensitive skin. It has the ability to repair and maintain healthy barrier function by increasing skin resilience. Centella Asiatica Extract also improves skin elasticity and relieves dryness of the skin. We particularly like that there is a good concentration of Niacinamide (1.80% - 2.70%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.

Panthenol also called pro-vitamin B5 is both an emollient and humectant with exceptional moisturizing benefits. It helps strengthen the skin barrier and serves as a protection against environmental stressors. This is a high-performance ingredient that soothes the skin, providing instant relief to redness and irritation. Panthenol is a compound derived from pantothenic acid, an essential nutrient the body requires for various functions (like converting food into energy). When applied to the skin, it transforms into vitamin B5 and works as a humectant to attract and retain moisture. Just like hyaluronic acid. However, compared to its counterpart, panthenol is also an emollient, which means it works to soften the skin surface, reduce redness, and restore the skin’s barrier function. [1] At the moisturising stage of your routine (both AM and PM) squeeze a moderate amount out onto your fingers, and gently smooth the cream over your skin Panethol’s main benefit is that it helps to draw water into the skin. Acting as a humectant, panthenol binds to water molecules and holds them in the skin. Hydrated skin is able to function properly and is responsible for dewy, plumped-looking skin. This makes panthenol great for skin types that endure harsh climates or air conditioning and heating as it is able to compensate for some of the transepidermal water loss that occurs in these environments. Transepidermal water loss refers to the loss of moisture that occurs from our skin to the environment. As we age our skin’s ability to minimize water loss reduces, resulting in dehydrated skin. Dehydrated skin is often responsible for that dullness and matte look. Centella Asiatica Extract, Panthenol(10%), Squalane, Butylene Glycol, Water, 1,2-Hexanediol, Niacinamide, Hydrolyzed Jojoba Esters, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Hydroxyacetophenone, Tromethamine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Disodium EDTA, Xanthan Gum, Sodium Hyaluronate, Madecassoside, Asiaticoside, Asiatic Acid, Copper Tripeptide-1, Madecassic AcidNow it’s time to apply the panthenol-infused product. Take a small amount and gently massage it onto your skin. The slightly damp skin has better absorption power, so panthenol can penetrate deeper and provide more benefits. After applying panthenol, give it a few moments to fully absorb into your skin before following with other products. Panthenol products that we recommend Panthenol also helps to maintain a healthy skin barrier through its emollient action. The skin’s natural barrier consists of the first few layers of skin and the natural oils that the skin produces. The skin barrier protects the skin from water loss, bacteria, and allergens. Disruption of the skin barrier has been associated with skin conditions such as eczema , dermatitis , and psoriasis . It contains 10% Panthenol that helps moisturize, protect and strengthen the skin barrier. This formula also contains Centella Asiatica Extract to soothe the skin, Squalane to soften the skin, providing hydrating and calming effects. Lastly, our superhero Niacinamide (vitamin B3) will work on brightening the skin. Created especially for ultra-sensitive skin, this minimal cream is designed to repair and soothe areas of irritation with an ultra-gentle formula, free from fragrances and essential oils. A lso fortified with a calming blend of Centella and Squalene to help soothe areas of rednes s and provide intensive hydration. Cosmetic Ingredient Review, 1987. ‘Final Report on the Safety Assessment of Panthenol and Pantothenic Acid’, Journal of the American College of Toxicology, vol. 6, no.1.

Panthenol is considered to be safe for its indicated uses. Given that panthenol is generally well tolerated for most skin types and rarely causes irritation or sensitivity it is safe for use in most formulations. One of the biological activities of thecentellosides isto be able to stimulate GAGs(glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells), and especially hyaluronic acid synthesis in our skin. This is probably one of the reasons why Centella Asiatica Extract has nice skin moisturizingproperties that was confirmed by a 25 people, four weeks study along with Centella's anti-inflammatory effects. Madecassoside can also help in burn wound healing through increasing antioxidant activity and enhancing collagen synthesis. Asiaticoside was shown to increase antioxidant levels on rats skin when applied at 0.2%. Niacinamide is a form of Vitamin B-3 that has a range of benefits from preserving skin hydration and even protecting skin from environmental stressors. It also helps gently balance oil production and inflammatory responses, supporting the skin barrier and improving its texture.Panthenol is an emollient that interacts with the lipids (such as ceramides) that form the protective barrier on the outer layer of the skin. So it has the ability to restore barrier function and reduce transepidermal water loss, which means your skin can retain more moisture and combat dryness. Encourages skin recovery

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants. Panthenol isn’t just a moisture magnet; it’s also an anti-inflammatory agent. It can be effective in reducing redness caused by sun exposure or skin conditions, calming inflamed pimples, and relieving itchiness. Panthenol side effectsSqualane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life. Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane. Centella Asiatica Extract, Panthenol (10%), Squalane, Butylene Glycol, Water, 1,2-Hexanediol, Niacinamide, Hydrolyzed Jojoba Esters, Acrylates/​C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate/​VP Copolymer, Hydroxyacetophenone, Tromethamine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Disodium EDTA, Xanthan Gum, Sodium Hyaluronate, Madecassoside, Asiaticoside, Asiatic Acid, Copper Tripeptide-1, Madecassic Acid Panthenol is a common ingredient that is found in a number of hair and skin products because of its ability to attract moisture and build healthier skin and hair. Panthenol is a provitamin of B5 which means that the body will convert it into vitamin B5. Panthenol is a great ingredient for moisturizers, shampoos and conditions as it binds and holds water in the skin. Hydrated skin helps to improve the plumpness and visible elasticity of the skin. Keep an eye on: Look out for the concentration of panthenol in the product, most effective formulations will have around 5% panthenol in their product. What Are Panthenol’s Benefits?