Few pregnant women have been given Xyrem (sodium oxybate). This means data on its effects during pregnancy are limited and it is not recommended during pregnancy. If you inadvertently become pregnant while taking Xyrem, tell your doctor immediately. Misuse of Xyrem can cause breathing problems, seizure, loss of consciousness, or death. Xyrem is available only from a certified pharmacy. Do not allow anyone else to use your medication. Initial dose: Up to 4.5 g orally per day, divided and given as 2 equal doses with the first dose taken at bedtime and the second dose taken between 2.5 to 4 hours later Transcript: FDA Peripheral and Central Nervous System Drugs Advisory Committee Meeting". FDA. 6 June 2001. Initial dose: Up to 3 g orally per day, divided and given as 2 equal doses with the first dose taken at bedtime and the second dose taken between 2.5 to 4 hours later

The total nightly dosage of Xyrem is divided into two doses. Prepare both doses of Xyrem prior to bedtime. Prior to ingestion, each dose of Xyrem should be diluted with approximately ¼ cup (approximately 60 mL) of water in the empty pharmacy containers provided. Consume 2 capsules of Acetyl with a meal in the morning. To enhance cognitive function, take an additional 2 capsules in the early afternoon. Do not exceed 4 capsules in a 24-hour period. Aqua Collagen: Mix 1 scoop of Aqua Collagen with 8-10 oz (240-300 ml) of cold water or your preferred beverage. Stir well and consume daily. For optimal results, take on an empty stomach or between meals. OxyRem: OxyRem by EHPlabs is an advanced sleep formula that promotes REM deep sleep and is also a non-stimulant thermogenic fat burner. It has been designed to help you recover faster, feel more energy and burn fat - and it all starts with sleeping better with OxyRem! WHAT HAPPENS WHEN YOU SLEEP?You may have withdrawal symptoms if you stop using Xyrem suddenly. Ask your doctor before stopping the medicine. Amino Acid - L-Theanine is included can help with neurotransmitter production which may assist with reducing feelings of anxiety. L-Theanine may also assist with reducing appetite and improving sleep quality. In January 2017, the FDA approved the first generic sodium oxybate product for narcolepsy symptoms, which is also subject to the same REMS program conditions as the original. [51] By April 2017, seven companies had filed Abbreviated New Drug Applications (ANDAs) with the FDA to market generic versions of Xyrem, which resulted in Jazz Pharmaceuticals filing patent infringement cases against them. Hikma Pharmaceuticals had been the first company to file an ANDA and Jazz Pharmaceuticals settled with them in April 2017; under the agreement Hikma could begin selling an authorized generic in 2023 under Jazz Pharmaceuticals' REMS, and would have five years of exclusivity, however, those conditions could change if Jazz Pharmaceuticals' patents were invalidated. [52] [53] In 2023, Jazz Pharmaceuticals licensed the right to produce an authorized generic of Xyrem to Hikma Pharmaceuticals, marketed as "Sodium Oxybate Oral Solution". [54] [55] Maintenance dose: The dose may be increased by 1 g (OR 0.5 g/dose) orally per night at 1 to 2-week intervals up to 6 g/day. Nonbenzodiazepines (e.g., β-carbolines (e.g., abecarnil), cyclopyrrolones (e.g., zopiclone), imidazopyridines (e.g., zolpidem), pyrazolopyrimidines (e.g., zaleplon))

OxySleep Collagen Night Time Shred is a delicious dairy and gluten free collagen-based powder, designed to be taken as a night-time beverage. GHB: A Club Drug To Watch" (PDF). Substance Abuse Treatment Advisory. 2 (1). November 2002. Archived from the original (PDF) on 2017-08-01 . Retrieved 2018-04-16. Chromium, Raspberry Ketones, L-Theanine, and Alpha Lipoic Acid contribute to blood sugar balance and heightened metabolic activity. OxyRem Night Fat Burner for Women is a bedtime fat burning, non-stimulant thermogenic scientifically formulated to promote Rapid Eye Movement (REM) deep sleep, while also curbing your appetite and boosting your metabolism. In 2023, the first authorized generic of Xyrem was made available in the US. [55] Research [ edit ]Institute of Medicine; National Research Council (US) Committee on the Framework for Evaluating the Safety of Dietary Supplements (2002). "Appendix D: Table of Food and Drug Administration Actions on Dietary Supplements". Proposed Framework for Evaluating the Safety of Dietary Supplements: For Comment. National Academies Press (US). In October 2011, the FDA sent Jazz Pharmaceuticals another FDA warning letter for failing to collect, evaluate, and promptly report adverse effects to the FDA after it started marketing the drug. [48] It sent another letter in 2013 saying that the problems described in the 2011 letter appeared to be resolved. [50] Alshaikh MK, Tricco AC, Tashkandi M, Mamdani M, Straus SE, BaHammam AS (August 2012). "Sodium oxybate for narcolepsy with cataplexy: systematic review and meta-analysis". Journal of Clinical Sleep Medicine. 8 (4): 451–458. doi: 10.5664/jcsm.2048. PMC 3407266. PMID 22893778. A very good product that does exactly what it’s supposed to do. I’m sleeping a lot better now and no longer wake up during the night.” OxyRem For Women Side Effects and Health Considerations As of April 2018, sodium oxybate is sold under the following brands: Alcover (Italy), Gamma-OH (France), Natrii oxybutyras Kalceks (Latvia), Somsanit (Germany), Xyrem (many countries by Jazz Pharmaceuticals and UCB). [1]

Xyrem is not a narcotic. Narcotics bind to opioid receptors in the brain and include substances such as codeine, oxycodone, and morphine.FDA Drug Safety Communication: Warning against use of Xyrem (sodium oxybate) with alcohol or drugs causing respiratory depression

Kane N (May 2017). "Sodium oxybate for the treatment of narcolepsy with cataplexy in adults" (PDF). NHS Regional Drug & Therapeutics Centre (Newcastle). Archived from the original (PDF) on 2020-10-21 . Retrieved 2018-04-14. Sleep can be roughly divided into two categories: REM (rapid eye movement) Sleep and NREM (non-rapid eye movement) Sleep. Both are important, and work together in a pattern that repeats itself until you wake up.

OxyRem For Women Benefits

Melatonin: The hormone that tells your brain it’s time to sleep. In the body it’s manufactured by the pineal gland. Supplement manufacturer’s generally obtain it from animal glands, but it’s also possible to make it in a lab. Xyrem (sodium oxybate) Information". Center for Drug Evaluation and Research. U.S. Food and Drug Administration. 25 January 2017. Trace Mineral Foundation Blend: The marketing information does not explain what this blend contains. It’s probably just some extra minerals to help improve the health. Xyrem is a Schedule III controlled substance. The active ingredient of Xyrem, sodium oxybate or gamma-hydroxybutyrate (GHB), is a Schedule I controlled substance. Abuse of illicit GHB, either alone or in combination with other CNS depressants, is associated with CNS adverse reactions, including seizure, respiratory depression, decreases in the level of consciousness, coma, and death. The rapid onset of sedation, coupled with the amnestic features of Xyrem, particularly when combined with alcohol, has proven to be dangerous for the voluntary and involuntary user (e.g., assault victim). Because illicit use and abuse of GHB have been reported, physicians should carefully evaluate patients for a history of drug abuse and follow such patients closely, observing them for signs of misuse or abuse of GHB (e.g., increase in size or frequency of dosing, drug-seeking behavior, feigned cataplexy) [see Drug Abuse and Dependence ( 9.2)]. Xyrem ® (sodium oxybate) is the sodium salt of gamma-hydroxybutyrate (GHB). Abuse or misuse of illicit GHB, either alone or in combination with other CNS depressants, is associated with CNS adverse reactions, including seizure, respiratory depression, decreases in the level of consciousness, coma, and death [see Warnings and Precautions ( 5.2)].