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The Impact of Peripheral Cooling on Chemotherapy-Induced

Similar benefit after subsequent chemo cycles (odds ratio: 0.59; 95% CI = 0.46–0.76, p< .0001), although analysis of impact of preexisting peripheral neuropathy not performed in statistics for late peripheral neuropathy group As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, Sato J., Mori M., Nihei S., Kumagai M., Takeuchi S., Kashiwaba M., & Kudo K. (2016). The effectiveness of regional cooling for paclitaxel-induced peripheral neuropathy. Journal of Pharmaceutical Health Care and Sciences, 2, Article number: 33 The Impact of Peripheral Cooling on Chemotherapy-Induced Peripheral Neuropathy: An Integrative Review - PMCEvaluate efficacy of compression with surgical gloves to prevent nanoparticle albumin-bound paclitaxel-associated peripheral neuropathy Reduced incidence of ≥ grade 2 peripheral neuropathy in the intervention group (5.0%–9.1%) vs. the control group (22.5%–35.8%); p< .05 at the fourth cycle and p< .01 after the fifth cycle Hanai A., Ishiguro H., Sozu T., Tsuda M., Yano I., Nakagawa T.,...Tsuboyama T. (2018). Effects of cryotherapy on objective and subjective symptoms of paclitaxel-induced neuropathy: Prospective self-controlled trial. Journal of the National Cancer Institute, 110( 2), 141–148. 10.1093/jnci/djx178 [ PMC free article] [ PubMed] [ CrossRef] [ Google Scholar] Komen M. M., Smorenburg C. H., van den Hurk C. J., & Nortier J. W. (2013). Factors influencing the effectiveness of scalp cooling in the prevention of chemotherapy-induced alopecia. Oncologist, 18( 7), 885–891. https://dx.doi.org/10.1634%2Ftheoncologist.2012-0332 [ PMC free article] [ PubMed] [ Google Scholar]

Frozen Socks - Etsy UK

Occurrence of Patient Neurotoxicity Questionnaire grades D or E peripheral neuropathy reduced with intervention (hand: 2.8% vs. 41.7%, p< .001; foot: 2.8 vs. 36.1%, p< .001) One of the two studies that applied a relatively lesser amount of cooling as defined in this review achieved statistically significant benefits in the severity of peripheral neuropathy ( Tsuyuki et al., 2016). This prospective, self-controlled study included 42 breast cancer patients who received compression therapy with two surgical gloves sized one size too small worn on the dominant hand, which resulted in a decrease in fingertip temperature on the intervention side. Subjects received nab-paclitaxel every 3 weeks for four cycles. Outcomes were measured using the CTCAE and the PNQ and were recorded at baseline, before each treatment cycle, and 1 week after nab-paclitaxel was administered. CTCAE results demonstrated a decrease in the incidence of ≥ grade 2 peripheral neuropathy on the intervention side ( p< .0001). The occurrence of ≥ grade 2 sensory neurotoxicity decreased from 76.1% to 21.4%, and that of motor neurotoxicity decreased from 57.1% to 26.2%. Patient Neuropathy Questionnaire results demonstrated significantly lower grades of peripheral neuropathy on the intervention side ( p< .0001).Compound motor action potential amplitudes of motor nerves more preserved at 3 months post treatment. Did not achieve statistical significance. Extensor digitorum brevis compound motor action potential amplitudes more preserved on intervention side below fibula head ( p = .07) and above fibula head ( p = .10). Pérez Fidalgo J. A., García Fabregat L., Cervantes A., Margulies A., Vidall C., & Roila F. (2012). Management of chemotherapy extravasation: ESMO-EONS Clinical Practice Guidelines. Annals of Oncology, 23( Suppl 7), vii167–vii173. 10.1093/annonc/mds294 [ PubMed] [ CrossRef] [ Google Scholar] Scotte F., Tourani J. M., Banu E., Peyromaure M., Levy E., Marsan S.,...Oudard S. (2005). Multicenter study of a frozen glove to prevent docetaxel-induced onycholysis and cutaneous toxicity of the hand. Journal of Clinical Oncology, 23( 19), 4424–4429. 10.1200/JCO.2005.15.651 [ PubMed] [ CrossRef] [ Google Scholar]