Medicine in a Minute

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Highly recommend this book to students especially clinical years and finals!""I really like the layout and simple nature of this textbook. It covers all of the major topics in medicine and doesn't give you any waffle."

As blood moves from the left atrium to the left ventricle, it flows through the mitral valve, which has anterior and posterior mitral valve leaflets With the advent of high-sensitivity troponin assays, very low levels of troponin can be detected. While these newer assays improve diagnostic sensitivity, they are likely to affect clinical specificity. This is primarily because troponin can be elevated in several other conditions: acute heart failure, myocarditis, pericarditis, pulmonary embolism, renal failure and sepsis.

Adult Treatment Panel (ATP III) Guidelines

Note that in clinical practice both types of heart failure often occur simultaneously, which is termed congestive cardiac failure. Investigations GTN: may be given via the sublingual or buccal route – if minimal to no response, an IV infusion may be considered; note that GTN should be avoided if systolic BP <90mmHg I really like the layout and simple nature of this textbook. It covers all of the major topics in medicine and doesn't give you any waffle." One of the newest agents to emerge in the past few years is the combination tablet valsartan/sacubitril. Two major trials, PARADIGM-HF and PARAMOUNT, were instrumental in establishing that combination therapy with valsartan/sacubitril improves mortality and is far more effective in reducing frequency of admissions than enalapril therapy alone. This was seen in both HFrEF and HFpEF. Sacubitril, the newer agent, is an angiotensin receptor neprilysin inhibitor (ARNI), which exerts its effects by causing increased peptide degradation and promoting natriuresis. 1.4 Hypertension

Ultrasound allows the physician to visualise the heart and assess its function; may be in two or three dimensions

He was laying on his side in the recovery position with his eyes closed. A few drops of blood that had come from his mouth and was coagulated on the floor. He was grey in colour, on the right side of his face, which was facing upwards, was a deep purple mark, on his forehead/cheek, that looked like a bruise. Was told to compressions until the ambul ... Anticoagulants interfere with prothrombotic mediators in the coagulation cascade. Warfarin inhibits the synthesis of Vitamin K dependent clotting factors (II, VII, IX and X). Novel oral anticoagulants (NOACs), such as apixaban, dabigatran and rivaroxaban, are used increasingly as they do not require therapeutic monitoring. However, these medications have no direct antidote, except for dabigatran. The FDA approved idarucizumab as an antidote in 2015. Patients who are able to carry out physical activity may be advised to resume sexual activity on a case-by-case basis My mother is given AKT4 kit to treat pulmonary TB which are of very high dosage but we notice after started taking medicines for a week, she is feeling fully tiered morning and night, dizziness and itchy skin at night. She was not like this before medicines. So are these side effects of TB drugs? Do we need to reduce dosage? She has bp and no sugar ... For instance, in 2016 a group of scientists from France published an article in the Journal of Clinical Oncology in which they summarized the results of their clinical trial on patients with metastatic colorectal cancer (cancer of large bowel in the IV stage of the disease – with metastases). The group that was treated with an individually adjusted dose of fluorouracil (antimetabolite drug used in the treatment of many cancers, including colon cancer) had a better response to the therapy, a higher survival rate and a lower grade of toxicity, than those treated with standard doses.