Psychedelics Encyclopedia

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Barker, S.A.; McIlhenny, E.H.; Strassman, R. A critical review of reports of endogenous psychedelic N, N-dimethyltryptamines in humans: 1955–2010. Drug Test. Anal. 2012, 4, 617–635. with the human organism-and possibly has even evolved into a harmonious relationship between human beings and the sentient fields of energy

Richards, W.A.; Rhead, J.C.; Dileo, F.B.; Yensen, R.; Kurland, A.A. The Peak Experience Variable in DPT-Assisted Psychotherapy with Cancer Patients. J. Psychedelic Drugs 1977, 9, 1–10. George, O.; Koob, G.F. Individual differences in prefrontal cortex function and the transition from drug use to drug dependence. Neurosci. Biobehav. Rev. 2010, 35, 232–247. Ramaekers, J.G.; Hutten, N.; Mason, N.L.; Dolder, P.; Theunissen, E.L.; Holze, F.; Liechti, M.E.; Feilding, A.; Kuypers, K.P. A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers. J. Psychopharmacol. 2021, 35, 398–405. Barker, S.A.; Monti, J.A.; Christian, S.T. Metabolism of the hallucinogen N,N-dimethyltryptamine in rat brain homogenates. Biochem. Pharmacol. 1980, 29, 1049–1057.Passie, T.; Halpern, J.H.; Stichtenoth, D.O.; Emrich, H.M.; Hintzen, A. The pharmacology of lysergic acid diethylamide: A review. CNS Neurosci. Ther. 2008, 14, 295–314.

Majić, T.; Jungaberle, H.; Schmidt, T.T.; Zeuch, A.; Hermle, L.; Gallinat, J. Psychotherapy with Adjuvant use of Serotonergic Psychoactive Substances: Possibilities and Challenges. Fortschr. Neurol. Psychiatr. 2017, 85, 383–392.

Don’t trip? Or maybe do

but nonetheless extremely valuable. A typical response is sometimes expressed in a statement like, "This experience is not exactly pleasant-but

cultures now thought by many to have been largely matriarchal or "partnership" -based in social structure. (It is worth noting in this context that in Mitchell, J.M.; Bogenschutz, M.; Lilienstein, A.; Harrison, C.; Kleiman, S.; Parker-Guilbert, K.; Ot’alora, G.M.; Garas, W.; Paleos, C.; Gorman, I. MDMA-assisted therapy for severe PTSD: A randomized, double-blind, placebo-controlled phase 3 study. Nat. Med. 2021, 27, 1025–1033. Masters, Ph.D., and Jean Houston, Ph.D., had a vast impact on the understanding of psychedelics through the publication of a popular book titled

Parker 44 notes that a participant’s increased sensitivity to subtle influences under psychedelics is both a boon and a bane to research. Luke 45 points out that the qualities that make such research alluring also make for poor test participants, as they may become engrossed in one or more aspects of the experience – the aesthetic rapture, 46 the quest for philosophical knowledge, 47 soul-searching self-examination, 48 their personal drama 49– or simply in observing the flow of their thoughts. 50 In addition, participants may struggle to find adequate ways to describe 51 the overwhelming flood of ideas and emotions, 52 and the speed of change of the internal experience. 53 The experience of dissociation (for instance with ketamine) can also hinder communication when participants are no longer present or aware of their physical environment, and, as Huxley notes 54, there is a need to reassure participants of their very identity once constructs of space and time disappear.

Stokes, D.M. (1997). Spontaneous psi phenomena. In Advances in Parapsychological Research 8, ed. by S. Krippner, 6-87. Jefferson, North Carolina, USA: McFarland. Leary, T., Litwin. G. H., & Metzner, R. (1963). Reactions to psilocybin administered in a supportive environment. Journal of Nervous and Mental Disease 137, 561-73. affirmation of the validity and relevance of the psychedelic experience. Fractals have been found to be accurate representations of Prue, B. Indigenous Supports for Recovery from Alcoholism and Drug Abuse: The Native American Church. J. Ethn. Cult. Divers. Soc. Work 2013, 22, 271–287.

The wild world of psychedelics

Tinoco, C.A. (1994). Testa de ESP em pacientes sob efeito da ayahuasca [Controlled ESP test in patients under the influence of ayahuasca]. Revista Brasileira de Parapsicologia 14, 42-8. Newcomer, J.W.; Hennekens, C.H. Severe mental illness and risk of cardiovascular disease. JAMA 2007, 298, 1794–1796.