Turmeric Powder (500g, 1.1 lb), Curcuma 100% Natural, min. of 3% curcuminoids Laboratory Tested, Gently Dried and Ground Turmeric Root, No additives, Vegan

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Turmeric contains curcumin. Curcumin might lower blood sugar. Glyburide is also used to lower blood sugar. Taking curcumin or turmeric along with glyburide might cause your blood sugar to go too low. Monitor your blood sugar closely. Your dose of glyburide might need to be changed. Pungcharoenkul, K. and Thongnopnua, P. Effect of different curcuminoid supplement dosages on total in vivo antioxidant capacity and cholesterol levels of healthy human subjects. Phytother Res 2011;25(11):1721-1726. View abstract. Peschel, D., Koerting, R., and Nass, N. Curcumin induces changes in expression of genes involved in cholesterol homeostasis. J Nutr.Biochem. 2007;18(2):113-119. View abstract. Naz, R. K. Can curcumin provide an ideal contraceptive? Mol.Reprod.Dev 2011;78(2):116-123. View abstract. Peeyush, K. T., Gireesh, G., Jobin, M., and Paulose, C. S. Neuroprotective role of curcumin in the cerebellum of streptozotocin-induced diabetic rats. Life Sci. 11-4-2009;85(19-20):704-710. View abstract.

Shoba, G., Joy, D., Joseph, T., Majeed, M., Rajendran, R., and Srinivas, P. S. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 1998;64(4):353-356. View abstract. Additionally, not all commercial turmeric powders are pure. Some are adulterated. This means that cheaper and potentially toxic ingredients have been added and are not listed on the label. Shu, J. C., He, Y. J., Lv, X., Ye, G. R., and Wang, L. X. Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells. J Nat.Med. 2009;63(4):415-420. View abstract.Sood, A., Mathew, R., and Trachtman, H. Cytoprotective effect of curcumin in human proximal tubule epithelial cells exposed to shiga toxin. Biochem.Biophys.Res Commun. 4-27-2001;283(1):36-41. View abstract. Khajehdehi, P., Zanjaninejad, B., Aflaki, E., Nazarinia, M., Azad, F., Malekmakan, L., and Dehghanzadeh, G. R. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. J Ren Nutr 2012;22(1):50-57. View abstract. However, one older review concluded that doses of 3,600–8,000 mg per day do not cause any serious side effects. Another study showed that single doses of 12,000 mg were well tolerated ( 31, 39). Perez-Arriaga, L., Mendoza-Magana, M. L., Cortes-Zarate, R., Corona-Rivera, A., Bobadilla-Morales, L., Troyo-Sanroman, R., and Ramirez-Herrera, M. A. Cytotoxic effect of curcumin on Giardia lamblia trophozoites. Acta Trop. 2006;98(2):152-161. View abstract. Li, H., van Berlo, D., Shi, T., Speit, G., Knaapen, A. M., Borm, P. J., Albrecht, C., and Schins, R. P. Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line. Toxicol Appl.Pharmacol 2-15-2008;227(1):115-124. View abstract.

Srivastava, K. C., Bordia, A., and Verma, S. K. Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets. Prostaglandins Leuk Kheradpezhouh, E., Panjehshahin, M. R., Miri, R., Javidnia, K., Noorafshan, A., Monabati, A., and Dehpour, A. R. Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine. Eur.J Pharmacol 2-25-2010;628(1-3):274-281. View abstract.

Chatterjee, S., Variyar, P. S., and Sharma, A. Stability of lipid constituents in radiation processed fenugreek seeds and turmeric: role of phenolic antioxidants. J Agric.Food Chem. 10-14-2009;57(19):9226-9233. View abstract.

If you’re considering taking a new supplement, always talk with your doctor first to make sure they are aware and can point you toward any possible interactions with medications you’re already taking. Curcumin Mohammadi, A., Sahebkar, A., Iranshahi, M., Amini, M., Khojasteh, R., Ghayour-Mobarhan, M., and Ferns, G. A. Effects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trial. Phytother Res 2013;27(3):374-379. View abstract. Like turmeric, curcumin’s effects on the body may augment or interfere with the actions of some of the medications you are taking. Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Turmeric contains a chemical called curcumin, which might act like the hormone estrogen. In theory, this might have effects on hormone-sensitive conditions. Until more is known, use cautiously if you have a condition that might be made worse by exposure to hormones. Kim, H. J., Yoo, H. S., Kim, J. C., Park, C. S., Choi, M. S., Kim, M., Choi, H., Min, J. S., Kim, Y. S., Yoon, S. W., and Ahn, J. K. Antiviral effect of Curcuma longa Linn extract against hepatitis B virus replication. J Ethnopharmacol. 7-15-2009;124(2):189-196. View abstract.Curcuma is known for its potent antioxidant and anti-inflammatory properties. It may help reduce the risk of cancer, aid digestion, and improve cognitive abilities. Let us look at the most important Curcuma benefits. Provides Pain Relief Ramirez-Bosca, A., Soler, A., Carrion, M. A., Diaz-Alperi, J., Bernd, A., Quintanilla, C., Quintanilla, Almagro E., and Miquel, J. An hydroalcoholic extract of curcuma longa lowers the apo B/apo A ratio. Implications for atherogenesis prevention. Mech.Ageing Dev. 10-20-2000;119(1-2):41-47. View abstract. Curcumin stimulates bile production and promotes gallbladder health, which in turn contributes to overall digestive health. It is commonly recommended for gas, bloating and indigestion. It is especially recommended for anyone suffering from an inflammatory gastric disease, such as ulcerative colitis or gastritis. Relieves Symptoms of Osteoarthritis Bundy, R., Walker, A. F., Middleton, R. W., and Booth, J. Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: a pilot study. J Altern.Complement Med. 2004;10(6):1015-1018. View abstract. A new review from 2021 also found that taking doses of around 1,000 mg of curcumin per day did not lead to any apparent adverse effects ( 27).