Davis, M., Thomas, J., van de Velde, S., Boissy, Y., Dawson, T., Iveson, R., & Sutton, K. (2011, December). A novel cosmetic approach to treat thinning hair. British Journal of Dermatology, 165, S24-S30. Retrieved from If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it. Panthenol is used in skin care products to keep the skin soft, smooth and improve elasticity. It is also used in cosmetic products that focus on aiding the skin's healing processes. Egger, S. F., Huber-Spitzy, V., Alzner, E., Scholda, C., and Vecsei, V. P. Corneal wound healing after superficial foreign body injury: vitamin A and dexpanthenol versus a calf blood extract. A randomized double-blind study. Ophthalmologica 1999;213(4):246-249. View abstract.

Xu J, Patassini S, Begley P, et al. Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer's disease. Biochem Biophys Res Commun. 2020;527(3):676-681. View abstract. Panthenol can be found in the ingredients in hair conditioners or body wash. Panthenol is used commonly in skincare and cosmetic products. ‌ Gehring, W. and Gloor, M. Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study. Arzneimittelforschung. 2000;50(7):659-663. View abstract. Camargo FB Jr, Gaspar LR, Maia Campos PM. Skin moisturizing effects of panthenol-based formulations. J Cosmet Sci. 2011 Jul-Aug;62(4):361-70. PMID: 21982351. Roper, B., Kaisig, D., Auer, F., Mergen, E., and Molls, M. Theta-Cream versus Bepanthol lotion in breast cancer patients under radiotherapy. A new prophylactic agent in skin care? Strahlenther.Onkol. 2004;180(5):315-322. View abstract.Besides hydration, panthenol has anti-inflammatory benefits for the skin. This is how it differs from hyaluronic acid. Panthenol has soothing effects on the skin and has been used to treat wounds and bruises. 4. It repairs the skin barrier. Jerajani, H. R., Mizoguchi, H., Li, J., Whittenbarger, D. J., and Marmor, M. J. The effects of a daily facial lotion containing vitamins B3 and E and provitamin B5 on the facial skin of Indian women: a randomized, double-blind trial. Indian J.Dermatol.Venereol.Leprol. 2010;76(1):20-26. View abstract. As panthenol is a non-comedogenic humectant & emollient, it’s incredibly helpful for people with oily skin. If you have oily and dehydrated skin, look for an oil-free moisturizer that also contains vitamin B5. A 2020 review on the role of panthenol, or dexpanthenol, on wound healing states that it is excellent for post-procedural wounds, especially when used immediately after skin damage. Boosts skin barrier function

Helps with wound healing: Those same cells that boost skin barrier function are also important for wound healing, which is why panthenol is often used to for minor skin injuries. Fun fact: According to Chilukuri, tattoo artists often recommend that their clients use a moisturizing cream with panthenol after getting a tattoo.Panthenol is an emollient that interacts with the lipids (such as ceramides) that form the protective barrier on the outer layer of the skin. So it has the ability to restore barrier function and reduce transepidermal water loss, which means your skin can retain more moisture and combat dryness. Encourages skin recovery CIR Safety Review: The CIR Expert Panel reviewed studies that found that products containing Panthenol did not induce significant skin irritation or sensitization. Significant skin irritation was also not observed with 100% Panthenol. Based on ultraviolet light absorption data, the CIR Expert Panel did not considere Panthenol or Pantothenic Acid to be photoirritants or photosensitizers. Mutagenicity and carcinogenicity data were not available for the safety assessment of Panthenol and Pantothenic Acid. The low concentrations of use of these ingredients in cosmetics and personal care products and the requirement of vitamin B5 for normal metabolism, suggested that the dietary exposure levels of this ingredient would greatly exceed the amount that could be absorbed from cosmetic use. A salt of Pantothenic Acid, calcium pantothenate, did not cause developmental effects. Kehrl, W. and Sonnemann, U. [Dexpanthenol nasal spray as an effective therapeutic principle for treatment of rhinitis sicca anterior]. Laryngorhinootologie 1998;77(9):506-512. View abstract. Gobbels, M. and Gross, D. [Clinical study of the effectiveness of a dexpanthenol containing artificial tears solution (Siccaprotect) in treatment of dry eyes]. Klin.Monbl.Augenheilkd. 1996;209(2-3):84-88. View abstract. There are a number of benefits to using products that contain panthenol, but there are several misconceptions about it because it’s used in a wide variety of applications. The most common misnomer is that it causes a heavy buildup in hair that may contribute to dandruff and oily hair. However, hair care experts dispute this rumor and say that the elements of panthenol could not cause this problem.